Sound Blaster 16 ISA has the hardware FM synth OPL3 and the driver is named "Creative Music Synth ". The 220 is the address port for the driver. You'd be suprised. The driver makes as much of a difference as the synth itself. Try a Yamaha PCI card. It has the same OPL3 chip as the SB16. However, the sounds are very different -- all because the driver is different. IMHO Creative Music Synth is the best FM driver. Why does the driver make so much of a difference?